I guess the Illuminati's desire to screw with Augmented people spans dimensions.
Can you link us to the interviews?
Also during the 48 minute demo it was stated that the mantis blades were 'late game', so assuming the 2019 trailer is final then the entire 'mission' is probably either a prologue (which would mean after meeting deshawn and screwing around with jackie, the mission happens, we wake up with <insert childhood hero> and missing augments [it was stated our shit was broken/missing in the junkyard GUI], forcing us to go back from square one and build ourself up) or late-game (which doesn't fit since Jackie's car is ours as seen in the trailer, only way that happens is if Jackie dies early on).
I'm betting the mission happens soonish into the game, V gets pissed and starts trying to take revenge with the aid of <childhood hero> and Alt.